Scientists detect new COVID-19 variant resistant to vaccine

Omicron COVID-19 variant

New COVID-19 variant with a high number of mutations raises concerns about COVID-19 transmissions, triggering travel restrictions.

A new COVID-19 variant that is highly transmissible and resistant to vaccine, has been detected in South Africa.

According to an Aljazeera report, the discovery of the new COVID-19 variant with a high number of mutations raises concerns about COVID-19 transmissions, triggering travel restrictions.

South Africa’s National Institute for Communicable Diseases (NICD) said 22 positive cases of the new COVID-19 variant have been recorded in the country following genomic sequencing. News of the announcement broke on Thursday.

South Africa Health Minister, Joe Phaahla, was quoted by Aljazeera saying the new COVID-19 variant was behind an “exponential” increase in reported cases, making it “a major threat”.

The report says the new COVID-19 variant, called B.1.1.529, has a very unusual constellation of mutations, which are worrying because they could help it evade the body’s immune response and make it more transmissible, scientists have said.

According to the report, South African scientists have detected more than 30 mutations to the spike protein, the part of the virus that helps to create an entry point for the coronavirus to infect human cells.

Tulio de Oliveira, director of the KwaZulu-Natal Research and Innovation Sequencing Platform, said the variant has baffled experts. “It has a big jump in evolution, many more mutations than we expected,” de Oliveira said.

In comparison, the Beta and Delta variants respectively have three and two mutations. The latter originated in India and caused the devastating second wave last year.

“The one piece of good news is that it can be detected by a PCR test”, de Oliveira added.

The mutations are associated with increased antibody resistance, which makes the virus more contagious.

The World Health Organisation (WHO) said it is “closely monitoring” the reported variant and is expected to meet on Friday to determine if it should be designated a variant of “interest” or of “concern”.

COVID-19 vaccines are based on the original coronavirus spike protein, raising concerns that the new dramatically different spike protein could render vaccines less effective.

Maria Van Kerkhove, the head of Emerging Diseases and Zoonosis at WHO, said on Thursday that “the concern is that when you have so many mutations, it can have an impact on how the virus behaves.”

“It will take a few weeks for us to understand what impact this variant has on any potential vaccines,” Van Kerkhove added.

Any new variant that is able to evade vaccines or spread faster than the now-dominant Delta variant might pose a significant threat as the world emerges from the pandemic.

But Professor Helen Rees, of the WHO’s African Regional Immunization Technical Advisory Group, urged people not to panic.

“[Currently] we are trying to identify how widely spread this is. There will be a lot of work looking at: Is it more transmissible? Is it associated with any more severity of disease? Does it render the vaccines less effective?” Rees told Al Jazeera.

“In the meantime, our big request to the world, in terms of vaccinating the African region, is please get the vaccines out into the region because as we know variants don’t stay in one country,” she added.

The variant has spread rapidly through the Gauteng province of South Africa, home to the economic hub Johannesburg and the capital Pretoria.

A total of about 50 confirmed cases have been identified in South Africa, Hong Kong and Botswana. The confirmed cases in Botswana and Hong Kong were detected among travellers from South Africa.

In response, Britain banned all travel from the country and five other southern African nations, namely Botwsana, Eswatini, Lesotho, Namibia and Zimbabwe starting at noon local time on Friday.

Israel also announced on Thursday it was barring its citizens from travelling to South Africa. It also included Lesotho, Botswana, Zimbabwe, Mozambique, Namibia and Eswatini to its highest-risk travel list.

On Friday, the Israeli Health Ministry said a new coronavirus variant had been detected in traveler who returned from Malawi.

EU Commission chief Ursula von der Leyen also said the EU will aim to halt air travel from the southern African region.

“The Commission will propose, in close coordination with Member States, to activate the emergency brake to stop air travel from the southern African region due to the variant of concern B.1.1.529,” she said in a tweet.

Ishaya Ibrahim:
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